Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

It is becoming increasingly clear that the deepest problems currently exercising philosophers of mind arise from an ill-begotten ontology, in particular, a mistaken ontology of properties. After going through some preliminaries, we identify three doctrines at the heart of this mistaken ontology: (P) For each distinct predicate, “F”, there exists one, and only one, property, F, such that, if “F” is applicable to an object a, then “F” is applicable in virtue of a’s being F. (U) Properties are universals, not (...) particulars. (D) Every property is either categorical or dispositional, but not both. We show how these doctrines influence current philosophical thinking about the mind, suggest and defend an alternative conception of properties, and indicate how this conception provides answers to two puzzles besetting contemporary philosophy of mind: the problem of mental causation and the problem of qualia. (shrink)

This article documents how biomedical researchers in the United Kingdom understand and enact the idea of “openness.” This is of particular interest to researchers and science policy worldwide in view of the recent adoption of pioneering policies on Open Science and Open Access by the U.K. government—policies whose impact on and implications for research practice are in need of urgent evaluation, so as to decide on their eventual implementation elsewhere. This study is based on 22 in-depth interviews with U.K. researchers (...) in systems biology, synthetic biology, and bioinformatics, which were conducted between September 2013 and February 2014. Through an analysis of the interview transcripts, we identify seven core themes that characterize researchers’ understanding of openness in science and nine factors that shape the practice of openness in research. Our findings highlight the implications that Open Science policies can have for research processes and outcomes and provide recommendations for enhancing their content, effectiveness, and implementation. (shrink)

Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.

Table of contentsI1 Proceedings of the 4th World Conference on Research IntegrityConcurrent Sessions:1. Countries' systems and policies to foster research integrityCS01.1 Second time around: Implementing and embedding a review of responsible conduct of research policy and practice in an Australian research-intensive universitySusan Patricia O'BrienCS01.2 Measures to promote research integrity in a university: the case of an Asian universityDanny Chan, Frederick Leung2. Examples of research integrity education programmes in different countriesCS02.1 Development of a state-run “cyber education program of research ethics” in (...) KoreaEun Jung Ko, Jin Sun Kwak, TaeHwan Gwon, Ji Min Lee, Min-Ho LeeCS02.3 Responsible conduct of research teachers’ training courses in Germany: keeping on drilling through hard boards for more RCR teachersHelga Nolte, Michael Gommel, Gerlinde Sponholz3. The research environment and policies to encourage research integrityCS03.1 Challenges and best practices in research integrity: bridging the gap between policy and practiceYordanka Krastev, Yamini Sandiran, Julia Connell, Nicky SolomonCS03.2 The Slovenian initiative for better research: from national activities to global reflectionsUrsa Opara Krasovec, Renata SribarCS03.3 Organizational climate assessments to support research integrity: background of the Survey of Organizational Research Climate and the experience with its use at Michigan State UniversityBrian C. Martinson, Carol R. Thrush, C.K. Gunsalus4. Expressions of concern and retractionsCS04.1 Proposed guidelines for retraction notices and their disseminationIvan Oransky, Adam MarcusCS04.2 Watching retractions: analysis of process and practice, with data from the Wiley retraction archivesChris Graf, Verity Warne, Edward Wates, Sue JoshuaCS04.3 An exploratory content analysis of Expressions of ConcernMiguel RoigCS04.4 An ethics researcher in the retraction processMichael Mumford5. Funders' role in fostering research integrityCS05.1 The Fonds de Recherche du Québec’s institutional rules on the responsible conduct of research: introspection in the funding agency activitiesMylène Deschênes, Catherine Olivier, Raphaëlle Dupras-LeducCS05.2 U.S. Public Health Service funds in an international setting: research integrity and complianceZoë Hammatt, Raju Tamot, Robin Parker, Cynthia Ricard, Loc Nguyen-Khoa, Sandra TitusCS05.3 Analyzing decision making of funders of public research as a case of information asymmetryKarsten Klint JensenCS05.4 Research integrity management: Empirical investigation of academia versus industrySimon Godecharle, Ben Nemery, Kris Dierickx5A: Education: For whom, how, and what?CS05A.1 Research integrity or responsible conduct of research? What do we aim for?Mickey Gjerris, Maud Marion Laird Eriksen, Jeppe Berggren HoejCS05A.2 Teaching and learning about RCR at the same time: a report on Epigeum’s RCR poll questions and other assessment activitiesNicholas H. SteneckCS05A.4 Minding the gap in research ethics education: strategies to assess and improve research competencies in community health workers/promoteresCamille Nebeker, Michael Kalichman, Elizabeth Mejia Booen, Blanca Azucena Pacheco, Rebeca Espinosa Giacinto, Sheila Castaneda6. Country examples of research reward systems and integrityCS06.1 Improving systems to promote responsible research in the Chinese Academy of SciencesDing Li, Qiong Chen, Guoli Zhu, Zhonghe SunCS06.4 Exploring the perception of research integrity amongst public health researchers in IndiaParthasarathi Ganguly, Barna Ganguly7. Education and guidance on research integrity: country differencesCS07.1 From integrity to unity: how research integrity guidance differs across universities in Europe.Noémie Aubert Bonn, Kris Dierickx, Simon GodecharleCS07.2 Can education and training develop research integrity? The spirit of the UNESCO 1974 recommendation and its updatingDaniele Bourcier, Jacques Bordé, Michèle LeducCS07.3 The education and implementation mechanisms of research ethics in Taiwan's higher education: an experience in Chinese web-based curriculum development for responsible conduct of researchChien Chou, Sophia Jui-An PanCS07.4 Educating principal investigators in Swiss research institutions: present and future perspectivesLouis Xaver Tiefenauer8. Measuring and rewarding research productivityCS08.1 Altimpact: how research integrity underpins research impactDaniel Barr, Paul TaylorCS08.2 Publication incentives: just reward or misdirection of funds?Lyn Margaret HornCS08.3 Why Socrates never charged a fee: factors contributing to challenges for research integrity and publication ethicsDeborah Poff9. Plagiarism and falsification: Behaviour and detectionCS09.1 Personality traits predict attitude towards plagiarism of self and others in biomedicine: plagiarism, yes we can?Martina Mavrinac, Gordana Brumini, Mladen PetrovečkiCS09.2 Investigating the concept of and attitudes toward plagiarism for science teachers in Brazil: any challenges for research integrity and policy?Christiane Coelho Santos, Sonia VasconcelosCS09.3 What have we learnt?: The CrossCheck Service from CrossRefRachael LammeyCS09.4 High p-values as a sign of data fabrication/falsificationChris Hartgerink, Marcel van Assen, Jelte Wicherts10. Codes for research integrity and collaborationsCS10.1 Research integrity in cross-border cooperation: a Nordic exampleHanne Silje HaugeCS10.3 Research integrity, research misconduct, and the National Science Foundation's requirement for the responsible conduct of researchAaron MankaCS10.4 A code of conduct for international scientific cooperation: human rights and research integrity in scientific collaborations with international academic and industry partnersRaffael Iturrizaga11. Countries' efforts to establish mentoring and networksCS11.1 ENRIO : a network facilitating common approaches on research integrity in EuropeNicole FoegerCS11.2 Helping junior investigators develop in a resource-limited country: a mentoring program in PeruA. Roxana Lescano, Claudio Lanata, Gissella Vasquez, Leguia Mariana, Marita Silva, Mathew Kasper, Claudia Montero, Daniel Bausch, Andres G LescanoCS11.3 Netherlands Research Integrity Network: the first six monthsFenneke Blom, Lex BouterCS11.4 A South African framework for research ethics and integrity for researchers, postgraduate students, research managers and administratorsLaetus OK Lategan12. Training and education in research integrity at an early career stageCS12.1 Research integrity in curricula for medical studentsGustavo Fitas ManaiaCS12.2 Team-based learning for training in the responsible conduct of research supports ethical decision-makingWayne T. McCormack, William L. Allen, Shane Connelly, Joshua Crites, Jeffrey Engler, Victoria Freedman, Cynthia W. Garvan, Paul Haidet, Joel Hockensmith, William McElroy, Erik Sander, Rebecca Volpe, Michael F. VerderameCS12.4 Research integrity and career prospects of junior researchersSnezana Krstic13. Systems and research environments in institutionsCS13.1 Implementing systems in research institutions to improve quality and reduce riskLouise HandyCS13.2 Creating an institutional environment that supports research integrityDebra Schaller-DemersCS13.3 Ethics and Integrity Development Grants: a mechanism to foster cultures of ethics and integrityPaul Taylor, Daniel BarrCS13.4 A culture of integrity at KU LeuvenInge Lerouge, Gerard Cielen, Liliane Schoofs14. Peer review and its role in research integrityCS14.1 Peer review research across disciplines: transdomain action in the European Cooperation in Science and Technology “New Frontiers of Peer Review ”Ana Marusic, Flaminio SquazzoniCS14.2 Using blinding to reduce bias in peer reviewDavid VauxCS14.3 How to intensify the role of reviewers to promote research integrityKhalid Al-Wazzan, Ibrahim AlorainyCS14.4 Credit where credit’s due: professionalizing and rewarding the role of peer reviewerChris Graf, Verity Warne15. Research ethics and oversight for research integrity: Does it work?CS15.1 The psychology of decision-making in research ethics governance structures: a theory of bounded rationalityNolan O'Brien, Suzanne Guerin, Philip DoddCS15.2 Investigator irregularities: iniquity, ignorance or incompetence?Frank Wells, Catherine BlewettCS15.3 Academic plagiarismFredric M. Litto16. Research integrity in EuropeCS16.1 Whose responsibility is it anyway?: A comparative analysis of core concepts and practice at European research-intensive universities to identify and develop good practices in research integrityItziar De Lecuona, Erika Löfstrom, Katrien MaesCS16.2 Research integrity guidance in European research universitiesKris Dierickx, Noémie Bonn, Simon GodecharleCS16.3 Research Integrity: processes and initiatives in Science Europe member organisationsTony Peatfield, Olivier Boehme, Science Europe Working Group on Research IntegrityCS16.4 Promoting research integrity in Italy: the experience of the Research Ethics and Bioethics Advisory Committee of the Consiglio Nazionale delle Ricerche Cinzia Caporale, Daniele Fanelli17. Training programs for research integrity at different levels of experience and seniorityCS17.1 Meaningful ways to incorporate research integrity and the responsible conduct of research into undergraduate, graduate, postdoctoral and faculty training programsJohn Carfora, Eric Strauss, William LynnCS17.2 "Recognize, respond, champion": Developing a one-day interactive workshop to increase confidence in research integrity issuesDieter De Bruyn, Bracke Nele, Katrien De Gelder, Stefanie Van der BurghtCS17.4 “Train the trainer” on cultural challenges imposed by international research integrity conversations: lessons from a projectJosé Roberto Lapa e Silva, Sonia M. R. Vasconcelos18. Research and societal responsibilityCS18.1 Promoting the societal responsibility of research as an integral part of research integrityHelene IngierdCS18.2 Social responsibility as an ethical imperative for scientists: research, education and service to societyMark FrankelCS18.3 The intertwined nature of social responsibility and hope in scienceDaniel Vasgird, Stephanie BirdCS18.4 Common barriers that impede our ability to create a culture of trustworthiness in the research communityMark Yarborough19. Publication ethicsCS19.1 The authors' forum: A proposed tool to improve practices of journal editors and promote a responsible research environmentIbrahim Alorainy, Khalid Al-WazzanCS19.2 Quantifying research integrity and its impact with text analyticsHarold GarnerCS19.3 A closer look at authorship and publication ethics of multi- and interdisciplinary teamsLisa Campo-Engelstein, Zubin Master, Elise Smith, David Resnik, Bryn Williams-JonesCS19.4 Invisibility of duplicate publications in biomedicineMario Malicki, Ana Utrobicic, Ana Marusic20. The causes of bad and wasteful research: What can we do?CS20.1 From countries to individuals: unravelling the causes of bias and misconduct with multilevel meta-meta-analysisDaniele Fanelli, John PA IoannidisCS20.2 Reducing research waste by integrating systems of oversight and regulationGerben ter Riet, Tom Walley, Lex Marius BouterCS20.3 What are the determinants of selective reporting?: The example of palliative care for non-cancer conditionsJenny van der Steen, Lex BouterCS20.4 Perceptions of plagiarism, self-plagiarism and redundancy in research: preliminary results from a national survey of Brazilian PhDsSonia Vasconcelos, Martha Sorenson, Francisco Prosdocimi, Hatisaburo Masuda, Edson Watanabe, José Carlos Pinto, Marisa Palácios, José Lapa e Silva, Jacqueline Leta, Adalberto Vieyra, André Pinto, Mauricio Sant’Ana, Rosemary Shinkai21. Are there country-specific elements of misconduct?CS21.1 The battle with plagiarism in Russian science: latest developmentsBoris YudinCS21.2 Researchers between ethics and misconduct: A French survey on social representations of misconduct and ethical standards within the scientific communityEtienne Vergès, Anne-Sophie Brun-Wauthier, Géraldine VialCS21.3 Experience from different ways of dealing with research misconduct and promoting research integrity in some Nordic countriesTorkild VintherCS21.4 Are there specifics in German research misconduct and the ways to cope with it?Volker Bähr, Charité22. Research integrity teaching programmes and their challengesCS22.1 Faculty mentors and research integrityMichael Kalichman, Dena PlemmonsCS22.2 Training the next generation of scientists to use principles of research quality assurance to improve data integrity and reliabilityRebecca Lynn Davies, Katrina LaubeCS22.3 Fostering research integrity in a culturally-diverse environmentCynthia Scheopner, John GallandCS22.4 Towards a standard retraction formHervé Maisonneuve, Evelyne Decullier23. Commercial research and integrityCS23.1 The will to commercialize: matters of concern in the cultural economy of return-on-investment researchBrian NobleCS23.2 Quality in drug discovery data reporting: a mission impossible?Anja Gilis, David J. Gallacher, Tom Lavrijssen, Malwitz David, Malini Dasgupta, Hans MolsCS23.3 Instituting a research integrity policy in the context of semi-private-sector funding: an example in the field of occupational health and safetyPaul-Emile Boileau24. The interface of publication ethics and institutional policiesCS24.1 The open access ethical paradox in an open government effortTony SavardCS24.2 How journals and institutions can work together to promote responsible conductEric MahCS24.3 Improving cooperation between journals and research institutions in research integrity casesElizabeth Wager, Sabine Kleinert25. Reproducibility of research and retractionsCS25.1 Promoting transparency in publications to reduce irreproducibilityVeronique Kiermer, Andrew Hufton, Melanie ClyneCS25.2 Retraction notices issued for publications by Latin American authors: what lessons can we learn?Sonia Vasconcelos, Renan Moritz Almeida, Aldo Fontes-Pereira, Fernanda Catelani, Karina RochaCS25.3 A preliminary report of the findings from the Reproducibility Project: Cancer biologyElizabeth Iorns, William Gunn26. Research integrity and specific country initiativesCS26.1 Promoting research integrity at CNRS, FranceMichèle Leduc, Lucienne LetellierCS26.2 In pursuit of compliance: is the tail wagging the dog?Cornelia MalherbeCS26.3 Newly established research integrity policies and practices: oversight systems of Japanese research universitiesTakehito Kamata27. Responsible conduct of research and country guidelinesCS27.1 Incentives or guidelines? Promoting responsible research communication through economic incentives or ethical guidelines?Vidar EnebakkCS27.3 Responsible conduct of research: a view from CanadaLynn PenrodCS27.4 The Danish Code of Conduct for Research Integrity: a national initiative to promote research integrity in DenmarkThomas Nørgaard, Charlotte Elverdam28. Behaviour, trust and honestyCS28.1 The reasons behind non-ethical behaviour in academiaYves FassinCS28.2 The psychological profile of the dishonest scholarCynthia FekkenCS28.3 Considering the implications of Dan Ariely’s keynote speech at the 3rd World Conference on Research Integrity in MontréalJamal Adam, Melissa S. AndersonCS28.4 Two large surveys on psychologists’ views on peer review and replicationJelte WichertsBrett Buttliere29. Reporting and publication bias and how to overcome itCS29.1 Data sharing: Experience at two open-access general medical journalsTrish GrovesCS29.2 Overcoming publication bias and selective reporting: completing the published recordDaniel ShanahanCS29.3 The EQUATOR Network: promoting responsible reporting of health research studiesIveta Simera, Shona Kirtley, Eleana Villanueva, Caroline Struthers, Angela MacCarthy, Douglas Altman30. The research environment and its implications for integrityCS30.1 Ranking of scientists: the Russian experienceElena GrebenshchikovaCS30.4 From cradle to grave: research integrity, research misconduct and cultural shiftsBronwyn Greene, Ted RohrPARTNER SYMPOSIAPartner Symposium AOrganized by EQUATOR Network, Enhancing the Quality and Transparency of Health ResearchP1 Can we trust the medical research literature?: Poor reporting and its consequencesIveta SimeraP2 What can BioMed Central do to improve published research?Daniel Shanahan, Stephanie HarrimanP3 What can a "traditional" journal do to improve published research?Trish GrovesP4 Promoting good reporting practice for reliable and usable research papers: EQUATOR Network, reporting guidelines and other initiativesCaroline StruthersPartner Symposium COrganized by ENRIO, the European Network of Research Integrity OfficersP5 Transparency and independence in research integrity investigations in EuropeKrista Varantola, Helga Nolte, Ursa Opara, Torkild Vinther, Elizabeth Wager, Thomas NørgaardPartner Symposium DOrganized by IEEE, the Institute of Electrical and Electronics EngineersRe-educating our author community: IEEE's approach to bibliometric manipulation, plagiarism, and other inappropriate practicesP6 Dealing with plagiarism in the connected world: An Institute of Electrical and Electronics Engineers perspectiveJon RokneP7 Should evaluation of raises, promotion, and research proposals be tied to bibliometric indictors? What the Institute of Electrical and Electronics Engineers is doing to answer this questionGianluca SettiP8 Recommended practices to ensure conference content qualityGordon MacPhersonPartner Symposium EOrganized by the Committee on Freedom and Responsibility in the Conduct of Science of ICSU, the International Council for ScienceResearch assessment and quality in science: perspectives from international science and policy organisationsP9 Challenges for science and the problems of assessing researchEllen HazelkornP10 Research assessment and science policy developmentCarthage SmithP11 Research integrity in South Africa: the value of procedures and processes to global positioningRobert H. McLaughlinP12 Rewards, careers and integrity: perspectives of young scientists from around the worldTatiana Duque MartinsPartner Symposium FOrganized by the Online Resource Center for Ethics Education in Engineering and Science / Center for Engineering, Ethics, and Society of the National Academy of EngineeringP13 Research misconduct: conceptions and policy solutionsTetsuya Tanimoto, Nicholas Steneck, Daniele Fanelli, Ragnvald Kalleberg, Tajammul HusseinPartner Symposium HOrganized by ORI, the Office of Research Integrity; Universitas 21; and the Asia Pacific Research Integrity NetworkP14 International integrity networks: working together to ensure research integrityPing Sun, Ovid Tzeng, Krista Varantola, Susan ZimmermanPartner Symposium IOrganized by COPE, the Committee on Publication EthicsPublication without borders: Ethical challenges in a globalized worldP15 Authorship: credit and responsibility, including issues in large and interdisciplinary studiesRosemary ShinkaiPartner Symposium JOrganized by CITI, the Cooperative Institutional Training InitiativeExperiences on research integrity educational programs in Colombia, Costa Rica and PeruP16 Experiences in PeruRoxana LescanoP17 Experiences in Costa RicaElizabeth HeitmanP18 Experiences in ColumbiaMaria Andrea Rocio del Pilar Contreras NietoPoster Session B: Education, training, promotion and policyPT.01 The missing role of journal editors in promoting responsible researchIbrahim Alorainy, Khalid Al-WazzanPT.02 Honorary authorship in Taiwan: why and who should be in charge?Chien Chou, Sophia Jui-An PanPT.03 Authorship and citation manipulation in academic researchEric Fong, Al WilhitePT.04 Open peer review of research submission at medical journals: experience at BMJ Open and The BMJTrish GrovesPT.05 Exercising authorship: claiming rewards, practicing integrityDésirée Motta-RothPT.07 Medical scientists' views on publication culture: a focus group studyJoeri Tijdink, Yvo SmuldersPoster Session B: Education, training, promotion and policyPT.09 Ethical challenges in post-graduate supervisionLaetus OK LateganPT.10 The effects of viable ethics instruction on international studentsMichael Mumford, Logan Steele, Logan Watts, James Johnson, Shane Connelly, Lee WilliamsPT.11 Does language reflect the quality of research?Gerben ter Riet, Sufia Amini, Lotty Hooft, Halil KilicogluPT.12 Integrity complaints as a strategic tool in policy decision conflictsJanneke van Seters, Herman Eijsackers, Fons Voragen, Akke van der Zijpp and Frans BromPoster Session C: Ethics and integrity intersectionsPT.14 Regulations of informed consent: university-supported research processes and pitfalls in implementationBadaruddin Abbasi, Naif Nasser AlmasoudPT.15 A review of equipoise as a requirement in clinical trialsAdri LabuschagnePT.16 The Research Ethics Library: online resource for research ethics educationJohanne Severinsen, Espen EnghPT.17 Research integrity: the view from King Abdulaziz City for Science and TechnologyDaham Ismail AlaniPT. 18 Meeting global challenges in high-impact publications and research integrity: the case of the Malaysian Palm Oil BoardHJ. Kamaruzaman JusoffPT.19 University faculty perceptions of research practices and misconductAnita Gordon, Helen C. HartonPoster Session D: International perspectivesPT.21 The Commission for Scientific Integrity as a response to research fraudDieter De Bruyn, Stefanie Van der BurghtPT. 22 Are notions of the responsible conduct of research associated with compliance with requirements for research on humans in different disciplinary traditions in Brazil?Karina de Albuquerque Rocha, Sonia Maria Ramos de VasconcelosPT.23 Creating an environment that promotes research integrity: an institutional model of Malawi Liverpool Welcome TrustLimbanazo MatandikaPT.24 How do science policies in Brazil influence user-engaged ecological research?Aline Carolina de Oliveira Machado Prata, Mark William NeffPoster Session E: Perspectives on misconductPT.26 What “causes” scientific misconduct?: Testing major hypotheses by comparing corrected and retracted papersDaniele Fanelli, Rodrigo Costas, Vincent LarivièrePT.27 Perception of academic plagiarism among dentistry studentsDouglas Leonardo Gomes Filho, Diego Oliveira GuedesPT. 28 a few bad apples?: Prevalence, patterns and attitudes towards scientific misconduct among doctoral students at a German university hospitalVolker Bähr, Niklas Keller, Markus Feufel, Nikolas OffenhauserPT. 29 Analysis of retraction notices published by BioMed CentralMaria K. Kowalczuk, Elizabeth C. MoylanPT.31 "He did it" doesn't work: data security, incidents and partnersKatie SpeanburgPoster Session F: Views from the disciplinesPT.32 Robust procedures: a key to generating quality results in drug discoveryMalini Dasgupta, Mariusz Lubomirski, Tom Lavrijssen, David Malwitz, David Gallacher, Anja GillisPT.33 Health promotion: criteria for the design and the integrity of a research projectMaria Betânia de Freitas Marques, Laressa Lima Amâncio, Raphaela Dias Fernandes, Oliveira Patrocínio, and Cláudia Maria Correia Borges RechPT.34 Integrity of academic work from the perspective of students graduating in pharmacy: a brief research studyMaria Betânia de Freitas Marques, Cláudia Maria Correia Borges Rech, Adriana Nascimento SousaPT.35 Research integrity promotion in the Epidemiology and Health Services, the journal of the Brazilian Unified Health SystemLeila Posenato GarciaPT.36 When are clinical trials registered? An analysis of prospective versus retrospective registration of clinical trials published in the BioMed Central series, UKStephanie Harriman, Jigisha PatelPT.37 Maximizing welfare while promoting innovation in drug developmentFarida LadaOther posters that will be displayed but not presented orally:PT.38 Geoethics and the debate on research integrity in geosciencesGiuseppe Di Capua, Silvia PeppoloniPT.39 Introducing the Professionalism and Integrity in Research Program James M. DuBois, John Chibnall, Jillon Van der WallPT.40 Validation of the professional decision-making in research measureJames M. DuBois, John Chibnall, Jillon Van der Wall, Raymond TaitPT.41 General guidelines for research ethicsJacob HolenPT. 42 A national forum for research ethicsAdele Flakke Johannessen, Torunn EllefsenPT.43 Evaluation of integrity in coursework: an approach from the perspective of the higher education professorClaudia Rech, Adriana Sousa, Maria Betânia de Freitas MarquesPT.44 Principles of geoethics and research integrity applied to the European Multidisciplinary Seafloor and Water Column Observatory, a large-scale European environmental research infrastructureSilvia Peppoloni, Giuseppe Di Capua, Laura BeranzoliF1 Focus track on improving research systems: the role of fundersPaulo S.L. Beirão, Susan ZimmermanF2 Focus track on improving research systems: the role of countriesSabine Kleinert, Ana MarusicF3 Focus track on improving research systems: the role of institutionsMelissa S. Anderson, Lex Bouter. (shrink)

The concept of a proposition is important in several areas of philosophy and central to the philosophy of language. This collection of readings investigates many different philosophical issues concerning the nature of propositions and the ways they have been regarded through the years. Reflecting both the history of the topic and the range of contemporary views, the book includes articles from Bertrand Russell, Gottlob Frege, the Russell-Frege Correspondence, Alonzo Church, David Kaplan, John Perry, Saul Kripke, Hilary Putnam, Mark (...) Richard, Scott Soames, and Nathan Salmon. (shrink)

The U.S. stock market is one of the largest and most complex marketplaces in the global financial system. Over the past several decades, this market has evolved at multiple structural and temporal scales. New exchanges became active, and others stopped trading, regulations have been introduced and adapted, and technological innovations have pushed the pace of trading activity to blistering speeds. These developments have supported the growth of a rich machine-trading ecology that leads to qualitative differences in trading behavior at human (...) and machine time scales. We conduct a longitudinal analysis of comprehensive market data to quantify nonstationary dynamics throughout this system. We quantify the relationship between fluctuations in the number of active trading venues and realized opportunity costs experienced by market participants. We find that information asymmetries, in the form of quote dislocations, predict market-wide volatility indicators. Lastly, we uncover multiple micro-to-macro level pathways, including those exhibiting evidence of self-organized criticality. (shrink)

This is the first book to offer the best essays, articles, and speeches on ethics and intelligence that demonstrate the complex moral dilemmas in intelligence collection, analysis, and operations. Some are recently declassified and never before published, and all are written by authors whose backgrounds are as varied as their insights, including Robert M. Gates, former Director of the Central Intelligence Agency; John P. Langan, the Joseph Cardinal Bernardin Professor of Catholic Social Thought at the Kennedy Institute of Ethics, (...) Georgetown University; and Loch K. Johnson, Regents Professor of Political Science at the University of Georgia and recipient of the Owens Award for contributions to the understanding of U.S. intelligence activities. Creating the foundation for the study of ethics and intelligence by filling in the gap between warfare and philosophy, this is a valuable collection of literature for building an ethical code that is not dependent on any specific agency, department, or country. (shrink)

Contents:Acknowledgements Foreword (Lt. Ervin J. Rokke)Preface (Davis S. Alberts and Thomas Czerwinski)SETTING THE SCENEThe Simple and the Complex (Murray Gell-Mann)America in the World Today (Zbigniew Brzezinski)COMPLEXITY THEORY and NATIONAL SECURITY POLICYComplex Systems: The Role of Interactions (Robert Jervis)Many Damn Things Simultaneously: Complexity Theory and World Affairs (James N. Rosenau)Complexity, Chaos, and National Security Policy: Metaphors or Tools? (Alvin M. Saperstein)The Reaction to Chaos (Steven R. Mann)COMPLEXITY THEORY, STRATEGY, and OPERATIONSClausewitz, Nonlinearity, and the Importance of Imagery (Alan D. Beyerchen)Complexity and Organization (...) Management (Robert R. Maxfield)Command and (Out of) Control: The Military Implications of Complexity Theory (John F. Schmitt)Complexity Theory and Air Power (Steven M. Rinaldi)Chaos Theory and U. S. Military Strategy: A "Leapfrog" Strategy for U.S. Defense Policy (Michael J. Mazarr)Contributors EditorsBibliography. (shrink)

What is consciousness? How does the subjective character of consciousness fit into an objective world? How can there be a science of consciousness? In this sequel to his groundbreaking and controversial The Conscious Mind, David Chalmers develops a unified framework that addresses these questions and many others. Starting with a statement of the "hard problem" of consciousness, Chalmers builds a positive framework for the science of consciousness and a nonreductive vision of the metaphysics of consciousness. He replies to many (...) critics of The Conscious Mind, and then develops a positive theory in new directions. The book includes original accounts of how we think and know about consciousness, of the unity of consciousness, and of how consciousness relates to the external world. Along the way, Chalmers develops many provocative ideas: the " consciousness meter", the Garden of Eden as a model of perceptual experience, and The Matrix as a guide to the deepest philosophical problems about consciousness and the external world. This book will be required reading for anyone interested in the problems of mind, brain, consciousness, and reality. (shrink)

Inspired by Rudolf Carnap's Der Logische Aufbau Der Welt, David J. Chalmers argues that the world can be constructed from a few basic elements. He develops a scrutability thesis saying that all truths about the world can be derived from basic truths and ideal reasoning. This thesis leads to many philosophical consequences: a broadly Fregean approach to meaning, an internalist approach to the contents of thought, and a reply to W. V. Quine's arguments against the analytic and the a (...) priori. Chalmers also uses scrutability to analyze the unity of science, to defend a conceptual approach to metaphysics, and to mount a structuralist response to skepticism. Based on the 2010 John Locke lectures, Constructing the World opens up debate on central philosophical issues involving language, consciousness, knowledge, and reality. This major work by a leading philosopher will appeal to philosophers in all areas. This entry contains uncorrected proofs of front matter, chapter 1, and first excursus. (shrink)

According to comparativist theories of quantities, their intrinsic values are not fundamental. Instead, all the quantity facts are grounded in scale-independent relations like "twice as massive as" or "more massive than." I show that this sort of scale independence is best understood as a sort of metaphysical symmetry--a principle about which transformations of the non-fundamental ontology leave the fundamental ontology unchanged. Determinism--a core scientific concept easily formulated in absolutist terms--is more difficult for the comparativist to define. After settling on the (...) most plausible comparativist understanding of determinism, I offer some examples of physical systems that the comparativist must count as indeterministic although the relevant physical theory gives deterministic predictions. Several morals are drawn. In particular: comparativism is metaphysically contingent if true, and it is most natural for a comparativist to accept an at-at theory of motion. (shrink)

Salomón de la Selva (1893-1959) was a Nicaraguan writer/activist who authored many books of verse in Spanish, but only one in English: TropicalTown, And Other Poems (1918). Published in New York by John Lane–and regarded by Silvio Sirias as the first book of English verse published in the U.S.by a Latin American–Tropical Town exhibits a curious dynamic of avantgarde impulse: radically subversive in invoking counter-politics resisting U.S. colonial transnationalism, yet tending toward inherited, traditional aesthetic forms of poetry meant to (...) legitimize Selva’s Latin American identity with an impression of authority that contiguous Modernist experimental poetries could not. Through its sympathy for the U.S. immigrant’s nostalgia for homeland, coupled with express disapproval of U.S. international affairs, Tropical Town leaves a poetic record that challenges presuppositions about the integral relationships between ethos, aesthetics, and consciousness vis-à-vis assumed understandings of what constitutes radical poetry in the Modernist moment. (shrink)

The widely held picture of dynamical symmetry as surplus structure in a physical theory has many metaphysical applications. Here, I focus on its relevance to the question of which quantities in a theory represent fundamental natural properties.

SOCIAL JUSTICE by Davild Miller. Clarendon Press: O.U.P., 1976. viii+367pp. £8.50.

This essay critically examines the political philosophy of John Dewey in relation to U.S. imperialism in the Asia-Pacific. First, using the work of Louis Menand and Robert Brandom's critical refinement of it, the significance of U.S. imperialism for pragmatism is discussed. Second, the essay argues that Dewey's work reveals a structured and generative absence of reflection on the expansion of American racial hegemony across the Pacific in spite of Dewey's serious engagement with Asia and especially China. The configuration of (...) this absence can be traced to his antidemocratic philosophical rendering of the classic frontier chronology of the U.S. nation-state. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:NOTES AND DISCUSSIONS 161 2) You wish him to become what he is not, and no longer to be what he is now (literally: what he is now, no longer to be [283d 2-3]). 3) You wish for his death, since you wish him no longer to be (283d 5-6). The obvious way of dealing with this argument is to make precisely the distinction made by the author of (...) the Dissoi Logoi at V, 15: we should say to Dionysodorus, "Your conclusion that the friends of Cleinias wish for his death is the result of an illegitimate step: you went from 'you wish him not to be ignorant' to 'you wish him not to be'. To have made this step is to have ignored the distinction between existence with respect to some particular thing, i.e., ignorance, and existence in general." (A later critic might point out to Dionysodorus that he has confused the copulative and existential uses of the verb "to be.") It now becomes possible to return to the question, which of the two formulations, (a) or (b), does the author of the Dissoi Logoi presuppose? On the basis of the Euthydemus passage, it seems likely that he presupposed both. The conclusion of Dionysodorus' argument is (b), that Cleinias does not exist, but his conclusion is based upon (a) that Cleinias both is (ignorant) and is not (wise). The Euthydemus passage shows clearly that the words "if someone denies that the man exists" are considerably less of a non sequitur than might first appear. CONCLUSmN. The fallacy-solving distinction of Dissoi Logoi, u 15 was probably understood by Plato~ although not clearly formulated until Aristotle. How is this fact to be assimilated? Is the Dissoi Logoi (or at least this section) much later than has hitherto been presupposed? Or have scholars simply failed to credit its author with this important distinction? Until we have additional studies of the treatise, further discussion would be premature. ROSAMOND KENT SPRAGUE University o] South Carolina HUME'S A LETTER FROM A GENTLEMAN, A REVIEW NOTE In his biography of David Hume, E. C. Mossner notes that on May 21, 1745 there appeared in two Edinburgh newspapers the following advertisement: This Day will be published, and sold by the Booksellersin Town, A LETTER from a Gentlemanto his Friend at Edinburgh: containing some Observations on a Specimenof the PrinciplesconcerningRELIGION and MORALITY, said to be maintain 'd in a Booklately published,intituled, A Treatiseo] Human Nature, &c.I This Letter, Mossner discloses, was sent by David Hume to his friend Henry Home (later Lord Kames), and its publication was, he suggests, the "last 7A later passagein the Euthydemus, 293b ft.,in whichSocratesuses obstructive tactics when the sophistswish to movefrom "knowingx" to "knowingsimpliciter" seems to me to point in this direction.See R. K. Sprague,Plato's Use o] Fallacy (London, 1962),22-23, and passim on secundumquid. 1See The Li]e o] David Hume (Edinburgh: Thomas Nelson & Sons, Ltd., 1954), pp. 153162,esp.p. 160. 162 HISTORY OF PHILOSOPHY frantic effort" by Hume's friends to stem the rising opposition to his appointment to the vacant chair of Ethics and Pneumatical Philosophy at Edinburgh University. Mossner was obliged to report further, however, not only that this effort had been in vain, but also that what "may well constitute an important document in the further interpretation of some aspects of the Treatise" has "never been located." z Now a copy of the Letter has been located. It was purchased from a Birmingham bookseller in December, 1966, by the National Library of Scotland. And, with admirable celerity, a facsimile edition of it has been published by the Edinburgh University Press. Adding still further to the value of this important discovery is the accompanying Introduction which describes the events, parties, and personalities which occasioned the Letter. The editors tell us that John Pringle first offered to resign his chair of philosophy in June, 1744, two years after he had taken leave to accept the position of Physician-General to the British forces in Flanders. He sent his offer to John Coutts, Lord Provost of Edinburgh, and Courts, in turn, suggested to Hume that he apply. Had Pringle not delayed... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:'0". J.~·VleWS GETTING ONE'S HANDS DIRTY; OR, PRACTISING WHAT YOU TEACH DAVID HARLEY Finlayson House, 40 Dumfries Street Paris, Ont., Canada N3L 2c8 Brian Patrick Hendley.. Dewey, Russell, Whitehead: Philosophers as Educators. Carbondale and Edwardsville: Southern Illinois U. P., 1986. Pp. xxi, 177· US$19.95; paper $9·95· B rian Hendley's book is more than a well-written account of three eminent philosophers who wrote about and participated in educational theory (...) and reform. The author has in fact selected Dewey, Russell and Whitehead as three stallions to draw a chariot. The precise nature of this "chariot" is indicated in the chapter entitled "The Philosopher as Educator Today" appearing at the end of the book: My intention throughout has been to suggest a way out of the current impasse in the philosophy ofeducation by reopening a conversation regarding a more productive role for philosophers to play, rather than merely analyzing concepts and policing arguments. My claim has been that philosophers of education can learn from their past, that we can see in Dewey, Russell and Whitehead instances of a productive approach to educational problems through thought and action. (P. 105) Having said this, the structure and contents of Hendley's book fall squarely into place. Chapter One, entitled "The Reconstruction of the Philosophy of Education", argues that there is a crisis in the current state of educational philosophy. The ensuing three chapters are devoted individually to Dewey, Russell and Whitehead. The concluding chapter, resting upon the strength of the examples given of three constructive contributors to the field, suggests new directions for the philosophy of education. It is clear that Hendley's book is more than an interesting account of the practical and theoretical educational activities of three of the most influential philosophers of the twentieth century. Dewey, Russell and Whitehead are not gathered together between the. same covers in order to explore or present a detailed analysis of their theoretical similarities or who may have influenced Reviews 219 whom. Instead, one gathers that the author has selected them on the basis of his own admiration and preference rather than for any shared theories which connect them. The point is made, however, that the strongest common element, and the most significant one, is that each man had ideas about education, each was a philosopher, and each attempted to exert some practical influence upon the educational institutions and practices of the day. In short, Dewey, Russell and Whitehead were theorists who were prepared to get their hands dirty. Hendley argues that after the death of John Dewey in 1952 educational philosophy was neglected and· philosophers tended to pay less attention to education. The author goes on to suggest some renewed interest in the field on the grounds of contributions made to the fifty-fourth Yearbook of the National Society for the Study of Education in 1955 under the theme "Modern Philosophies and Education", a special issue of the Harvard Education Review published in 1956; the publication of Israel Scheffler's edited collection of readings entitled Philosophy and Education in 1958; and R. S. Peters' Inaugural Address given at London in 1963, and his publication of Ethics and Education in 1966. According to this argument, we witness a general lapse after the death of Dewey, a rekindling in the mid-1950S and a broader resurgence in the 1960s. On the basis of the author's own account, I think that it is very difficult to argue that Dewey's death initiated any period of calm or disinterestedness. Furthermore, it is very problematic to point to various yearbooks or publications as indicators. The point is that with the death of Dewey there were numerous contenders to fill his position as the pre-eminent American philosopher of education. The extent to which anyone has been able to do so is a different matter. What I believe Hendley is really trying to say here is implicit in his argument, namely, that after the death of Dewey, no philosopher of equal stature took his place. The reason why no candidate equal to the task emerged is also suggested by the author. Dewey, Russell and Whitehead are to be admired because they had the... (shrink)

If we divide our physical theories into theories of matter and theories of spacetime, quantum field theory is our most fundamental empirically successful theory of matter. As such, it has attracted increasing attention from philosophers over the past two decades, beginning to eclipse its predecessor theory of quantum mechanics in the philosophical literature. Here I survey some central philosophical puzzles about the theory's foundations.

Eleanor Knox has argued that our concept of spacetime applies to whichever structure plays a certain functional role in the laws (the role of determining local inertial structure). I raise two complications for this approach. First, our spacetime concept seems to have the structure of a cluster concept, which means that Knox's inertial criteria for spacetime cannot succeed with complete generality. Second, the notion of metaphysical fundamentality may feature in the spacetime concept, in which case spacetime functionalism may be uninformative (...) in the absence of answers to fundamental metaphysical questions like the substantivalist/relationist debate. (shrink)

We pose and resolve a puzzle about spontaneous symmetry breaking in the quantum theory of infinite systems. For a symmetry to be spontaneously broken, it must not be implementable by a unitary operator in a ground state's GNS representation. But Wigner's theorem guarantees that any symmetry's action on states is given by a unitary operator. How can this unitary operator fail to implement the symmetry in the GNS representation? We show how it is possible for a unitary operator of this (...) sort to connect the folia of unitarily inequivalent representations. This result undermines interpretations of quantum theory that hold unitary equivalence to be necessary for physical equivalence. (shrink)

Nature seems to be such that we can describe it accurately with quantum theories of bosons and fermions alone, without resort to parastatistics. This has been seen as a deep mystery: paraparticles make perfect physical sense, so why don’t we see them in nature? We consider one potential answer: every paraparticle theory is physically equivalent to some theory of bosons or fermions, making the absence of paraparticles in our theories a matter of convention rather than a mysterious empirical discovery. We (...) argue that this equivalence thesis holds in all physically admissible quantum field theories falling under the domain of the rigorous Doplicher–Haag–Roberts approach to superselection rules. Inadmissible parastatistical theories are ruled out by a locality-inspired principle we call charge recombination. 1 Introduction2 Paraparticles in Quantum Theory3 Theoretical Equivalence3.1 Field systems in algebraic quantum field theory3.2 Equivalence of field systems4 A Brief History of the Equivalence Thesis4.1 The Green decomposition4.2 Klein transformations4.3 The argument of Drühl, Haag, and Roberts4.4 The Doplicher–Roberts reconstruction theorem5 Sharpening the Thesis6 Discussion6.1 Interpretations of Quantum Mechanics6.2 Structuralism and haecceities6.3 Paraquark theories. (shrink)

It is sometimes claimed that string theory posits a fundamental ontology including extended mereological simples, either in the form of minimum-sized regions of space or of the strings themselves. But there is very little in the actual theory to support this claim, and much that suggests it is false. Extant string theories treat space as a continuum, and strings do not behave like simples.

What is the mind? Is consciousness a process in the brain? How do our minds represent the world? Philosophy of Mind: Classical and Contemporary Readings is a grand tour of writings on these and other perplexing questions about the nature of the mind. The most comprehensive collection of its kind, the book includes sixty-three selections that range from the classical contributions of Descartes to the leading edge of contemporary debates. Extensive sections cover foundational issues, the nature of consciousness, and the (...) nature of mental content. Three of the selections are published here for the first time, while many other articles have been revised especially for this volume. Each section opens with an introduction by the editor. Philosophy of Mind is suitable for students at all levels and also for general readers. (shrink)

The French philosopher Gilles Deleuze was one of the most innovative and revolutionary thinkers of the twentieth century. Author of more than twenty books on literature, music, and the visual arts, Deleuze published the first volume of his two-volume study of film, _Cinema 1: The Movement-Image_, in 1983 and the second volume, _Cinema 2: The Time-Image_, in 1985. Since their publication, these books have had a profound impact on the study of film and philosophy. Film, media, and cultural studies scholars (...) still grapple today with how they can most productively incorporate Deleuze's thought. The first new collection of critical studies on Deleuze's cinema writings in nearly a decade, _Afterimages of Gilles Deleuze's Film Philosophy_ provides original essays that evaluate the continuing significance of Deleuze's film theories, accounting systematically for the ways in which they have influenced the investigation of contemporary visual culture and offering new directions for research. Contributors: Raymond Bellour, Centre Nationale de Recherches Scientifiques; Ronald Bogue, U of Georgia; Giuliana Bruno, Harvard U; Ian Buchanan, Cardiff U; James K. Chandler, U of Chicago; Tom Conley, Harvard U; Amy Herzog, CUNY; András Bálint Kovács, Eötvös Loránd U; Patricia MacCormack, Anglia Ruskin U; Timothy Murray, Cornell U; Dorothea Olkowski, U of Colorado; John Rajchman, Columbia U; Marie-Claire Ropars-Wuilleumier, U Paris VIII; Garrett Stewart, U of Iowa; Damian Sutton, Glasgow School of Art; Melinda Szaloky, UC Santa Barbara. (shrink)

I advance a stipulational account of symmetry-to-reality inference, according to which symmetries are part of the content of theories. For a theory to have a certain symmetry is for the theory to stipulate that models related by the symmetry represent the same possibility. I show that the stipulational account compares positively with alternatives, including Dasgupta’s epistemic account of symmetry, Møller-Nielsen’s motivational account, and so-called formal and ontic accounts. In particular, the stipulational account avoids the problems Belot and Dasgupta have raised (...) against formal and ontic accounts of symmetry while retaining many of the advantages of these otherwise-attractive frameworks. (shrink)

I examine some problems standing in the way of a successful `field interpretation' of quantum field theory. The most popular extant proposal depends on the Hilbert space of `wavefunctionals.' But since wavefunctional space is unitarily equivalent to many-particle Fock space, two of the most powerful arguments against particle interpretations also undermine this form of field interpretation. IntroductionField Interpretations and Field OperatorsThe Wavefunctional InterpretationFields and Inequivalent Representations 4.1. The Rindler representation 4.2. Spontaneous symmetry breaking 4.3. Coherent representations The Fate of Fields (...) in Interacting QFTConclusions. (shrink)

A new argument is given for the thesis that only symmetry-invariant physical quantities are real. Non-invariant quantities are dynamically epiphenomenal in that they have no effect on the evolution of invariant quantities, and it is a significant theoretical vice to posit epiphenomenal quantities.

Comparativism--the view that comparative relations like mass ratios are fundamental and intrinsic values of quantities are not--faces a challenge from physics. In its standard form, comparativism predicts indeterminism in physical theories that are ordinarily understood as deterministic. I explore an option for saving comparativism from this objection: the introduction of "mixed" relations that compare values of unlike quantities. Although tenable, this revised version of comparativism lacks some of the theoretical virtues of the standard version.

The nature of antimatter is examined in the context of algebraic quantum field theory. It is shown that the notion of antimatter is more general than that of antiparticles. Properly speaking, then, antimatter is not matter made up of antiparticles—rather, antiparticles are particles made up of antimatter. We go on to discuss whether the notion of antimatter is itself completely general in quantum field theory. Does the matter–antimatter distinction apply to all field theoretic systems? The answer depends on which of (...) several possible criteria we should impose on the space of physical states. (shrink)

Eleanor Knox has argued that our concept of spacetime applies to whichever structure plays a certain functional role in the laws. I raise two objections to this inertial functionalism. First, it depends on a prior assumption about which coordinate systems defined in a theory are reference frames, and hence on assumptions about which geometric structures are spatiotemporal. This makes Knox’s account circular. Second, her account is vulnerable to several counterexamples, giving the wrong result when applied to topological quantum field theories (...) and parity- and time-asymmetric theories. I advance an alternative account on which our spacetime concept is a cluster concept. On this view, the notion of metaphysical fundamentality may feature in the cluster, in which case spacetime functionalism may be uninformative in the absence of answers to fundamental metaphysical questions like the substantivalist/relationist debate. (shrink)

Eleanor Knox has argued that our concept of spacetime applies to whichever structure plays a certain functional role in the laws. I raise two objections to this inertial functionalism. First, it depends on a prior assumption about which coordinate systems defined in a theory are reference frames, and hence on assumptions about which geometric structures are spatiotemporal. This makes Knox’s account circular. Second, her account is vulnerable to several counterexamples, giving the wrong result when applied to topological quantum field theories (...) and parity- and time-asymmetric theories. I advance an alternative account on which our spacetime concept is a cluster concept. On this view, the notion of metaphysical fundamentality may feature in the cluster, in which case spacetime functionalism may be uninformative in the absence of answers to fundamental metaphysical questions like the substantivalist/relationist debate. (shrink)

The phenomenon of broken spacetime symmetry in the quantum theory of infinite systems forces us to adopt an unorthodox ontology. We must abandon the standard conception of the physical meaning of these symmetries, or else deny the attractive “liberal” notion of which physical quantities are significant. A third option, more attractive but less well understood, is to abandon the existing (Halvorson-Clifton) notion of intertranslatability for quantum theories.

In Section I, I clarify turning point issues in the Phillips and Block debate about whether there is unconscious perception. These include questions about whether uptake of certain visual information is an individual or person level accomplishment, as required for genuine unconscious _perceiving_. Section II takes up a recent reorientation proposed in Block ( 2017 ) towards the question of whether there is unconscious perceiving, where we are to look for the pervasive role of unconscious perceiving in, perhaps especially, the (...) online control of everyday reaching and grasping. I point out that while this may well be a helpfully different approach to explore, it does not evade the central questions and challenges familiar from the prior debate between Phillips and Block. Section III reviews an approach summarized in Dehaene ( 2014 ), drawing from a range of measures of neural activity. Dehaene provides evidence of quite rich non-conscious perceptual system responses, some arguably individual or person level. But in a fairly thin or fragile way, absent taking up, in higher level assessment, the information encoded in initial visual response. Or that is the interpretation I argue for, in relating the Dehaene account to the Phillips and Block debate, in a way that illuminates the Phillips and Block discussions. An Appendix provides an overview of debates in the literature about the Goodale and Milner Two Visual Systems Hypothesis, that Block ( 2017 ) makes central appeal to. (shrink)

Comments and replies from the 2021 Eastern APA book symposium on Jill North's Physics, Structure, and Reality.

The hypothesis that belief aims at the truth has been used to explain three features of belief: (1) the fact that correct beliefs are true beliefs, (2) the fact that rational beliefs are supported by the evidence and (3) the fact that we cannot form beliefs.

Ted Sider has shown that my indeterminism argument for comparativist theories of quantity also applies to Mundy's absolutist theory. This is because Mundy's theory posits only "pure" relations, i.e. relations between values of the same quantity (between masses and other masses, or distances and other distances). It is straightforward to solve the problem by positing additional mixed relations.

The permutation symmetry of quantum mechanics is widely thought to imply a sort of metaphysical underdetermination about the identity of particles. Despite claims to the contrary, this implication does not hold in the more fundamental quantum field theory, where an ontology of particles is not generally available. Although permutations are often defined as acting on particles, a more general account of permutation symmetry can be formulated using superselection theory. As a result, permutation symmetry applies even in field theories with no (...) particle interpretation. The quantum mechanical account of permutations acting on particles is recovered as a special case. (shrink)

John Ogbu has studied minority education from a comparative perspective for over 30 years. The study reported in this book--jointly sponsored by the community and the school district in Shaker Heights, Ohio--focuses on the academic performance of Black American students. Not only do these students perform less well than White students at every social class level, but also less well than immigrant minority students, including Black immigrant students. Furthermore, both middle-class Black students in suburban school districts, as well as (...) poor Black students in inner-city schools are not doing well. Ogbu's analysis draws on data from observations, formal and informal interviews, and statistical and other data. He offers strong empirical evidence to support the cross-class existence of the problem. The book is organized in four parts: *Part I provides a description of the twin problems the study addresses--the gap between Black and White students in school performance and the low academic engagement of Black students; a review of conventional explanations; an alternative perspective; and the framework for the study. *Part II is an analysis of _societal and school factors_ contributing to the problem, including race relations, Pygmalion or internalized White beliefs and expectations, levelling or tracking, the roles of teachers, counselors, and discipline. *_Community factors_--the focus of this study--are discussed in Part III. These include the educational impact of opportunity structure, collective identity, cultural and language or dialect frame of reference in schooling, peer pressures, and the role of the family. This research focus does _not_ mean exonerating the system and blaming minorities, nor does it mean neglecting school and society factors. Rather, Ogbu argues, the role of community forces should be incorporated into the discussion of the academic achievement gap by researchers, theoreticians, policymakers, educators, and minorities themselves who genuinely want to improve the academic achievement of African American children and other minorities. *In Part IV, Ogbu presents a summary of the study's findings on community forces and offers recommendations--some of which are for the school system and some for the Black community. _Black American Students in an Affluent Suburb: A Study of Academic Disengagement_ is an important book for a wide range of researchers, professionals, and students, particularly in the areas of Black education, minority education, comparative and international education, sociology of education, educational anthropology, educational policy, teacher education, and applied anthropology. (shrink)

Supersymmetry in quantum physics is a mathematically simple phenomenon that raises deep foundational questions. To motivate these questions, I present a toy model, the supersymmetric harmonic oscillator, and its superspace representation, which adds extra anticommuting dimensions to spacetime. I then explain and comment on three foundational questions about this superspace formalism: whether superspace is a substance, whether it should count as spatiotemporal, and whether it is a necessary postulate if one wants to use the theory to unify bosons and fermions.

This paper is devoted to the investigation of term-definable connexive implications in substructural logics with exchange and, on the semantical perspective, in sub-varieties of commutative residuated lattices (FL ${}_{\scriptsize\mbox{e}}$ -algebras). In particular, we inquire into sufficient and necessary conditions under which generalizations of the connexive implication-like operation defined in [6] for Heyting algebras still satisfy connexive theses. It will turn out that, in most cases, connexive principles are equivalent to the equational Glivenko property with respect to Boolean algebras. Furthermore, we (...) provide some philosophical upshots like, e.g., a discussion on the relevance of the above operation in relationship with G. Polya’s logic of plausible inference, and some characterization results on weak and strong connexivity. (shrink)

This volume explores whether the concept of the common good might be retrieved and become central in contemporary religious social thought. Contributors include: Charles C. West, John J. Collins, Ralph McInerny; J. Philip Wogaman, Charles E. Curran, Richard John Neuhaus, Dennis P. McCann, Ernest Bartell, Michael Novak, Charles K. Wilber, John W. Cooper, Gar Alperovitz, Richard T. DeGeorge, Gerald Cavanagh, William J. Cunningham, Peter Mann, Bette Jean Bullert and David Vogel. Co-published with the Notre Dame Center (...) for Ethics and Religious Values in Business. (shrink)

For centuries, the processes of social differentiation associated with Modernity have often been thought to intensify the need for site-specific forms of role training and knowledge production, threatening the university’s survival either through fragmentation or through failure to adapt. Other lines of argument emphasize the extent to which the Modern system creates and relies on an integrated knowledge system, but most of the literature stresses functional differentiation and putative threats to the university. And yet over this period the university has (...) flourished. In our view, this seeming paradox is explained by the fact that modern society rests as much on universalistic cosmological bases as it does on differentiation. The university expands over recent centuries because – as it has from its religious origins – it casts cultural and human materials in universalistic terms. Our view helps explain empirical phenomena that confound standard accounts: the university’s extraordinary expansion and global diffusion, its curricular and structural isomorphism, and its relatively unified structure. All of this holds increasingly true after World War II, as national state societies made up of citizens are increasingly embedded in a world society constituted of empowered individuals. The redefinition of society in global and individual terms reduces nationally bounded models of nature and culture, extends the pool of university beneficiaries and investigators, and empowers the human persons who are understood to root it all. The changes intensify universalization and the university’s rate of worldwide growth. For the university’s knowledge and “knowers,” and for the pedagogy that joins them together, the implications are many. The emerging societal context intensifies longstanding processes of cultural rationalization and ontological elaboration, yielding great expansions in what can and should be known, and in who can and should know. These changes in turn alter the menu of approved techniques for joining knowledge and knower as one. The “knowledge society” that results is distinguished by the extraordinary degree to which the university is linked to society. But it is also distinguished by the degree to which society is organized around the university’s abstracted and universalized understandings of the world and its degree-certified graduates. (shrink)

This case study examines the circumstance of a patient who has clearly articulated non-treatment preferences and who then later becomes incapacitated. The patient's wife as well as a consulting physician both expressed a preference for full treatment at the time of this incapacity. The analysis of this circumstance is pertinent given misinformed beliefs by health care providers that once a patient is incapacitated, the family is free to override prior values and preferences. The analysis discusses the autonomy, beneficence, and virtue-based (...) considerations as to why a formerly capacitated patient who has not recanted his non-treatment preferences should be obeyed. (shrink)